Near-infrared molecular imaging of tumors via chemokine receptors CXCR4 and CXCR7

The chemokine CXCL12/SDF-1 and its receptors CXCR4 and CXCR7 play a major role in tumor invasion, proliferation and metastasis. Since both receptors are overexpressed on distinct tumor cells and on the tumor vasculature, we evaluated their potential as targets for detection of cancers by molecular i...

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Detalles Bibliográficos
Autores principales: Meincke, Manuela, Tiwari, Sanjay, Hattermann, Kirsten, Kalthoff, Holger, Mentlein, Rolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213350/
https://www.ncbi.nlm.nih.gov/pubmed/21735100
http://dx.doi.org/10.1007/s10585-011-9403-y