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Near-infrared molecular imaging of tumors via chemokine receptors CXCR4 and CXCR7
The chemokine CXCL12/SDF-1 and its receptors CXCR4 and CXCR7 play a major role in tumor invasion, proliferation and metastasis. Since both receptors are overexpressed on distinct tumor cells and on the tumor vasculature, we evaluated their potential as targets for detection of cancers by molecular i...
Autores principales: | Meincke, Manuela, Tiwari, Sanjay, Hattermann, Kirsten, Kalthoff, Holger, Mentlein, Rolf |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213350/ https://www.ncbi.nlm.nih.gov/pubmed/21735100 http://dx.doi.org/10.1007/s10585-011-9403-y |
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