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Distinguishing Driver and Passenger Mutations in an Evolutionary History Categorized by Interference
In many biological scenarios, from the development of drug resistance in pathogens to the progression of healthy cells toward cancer, quantifying the selection acting on observed mutations is a central question. One difficulty in answering this question is the complexity of the background upon which...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Genetics Society of America
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213378/ https://www.ncbi.nlm.nih.gov/pubmed/21900272 http://dx.doi.org/10.1534/genetics.111.133975 |