The C313Y Piedmontese mutation decreases myostatin covalent dimerisation and stability

BACKGROUND: Myostatin is a key negative regulator of muscle growth and development, whose activity has important implications for the treatment of muscle wastage disorders. Piedmontese cattle display a double-muscled phenotype associated with the expression of C313Y mutant myostatin. In vivo, C313Y...

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Detalles Bibliográficos
Autores principales: Starck, Carlene S, Sutherland-Smith, Andrew J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213697/
https://www.ncbi.nlm.nih.gov/pubmed/22023879
http://dx.doi.org/10.1186/1756-0500-4-442

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213697/
https://www.ncbi.nlm.nih.gov/pubmed/22023879
http://dx.doi.org/10.1186/1756-0500-4-442

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