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Regulation of monocyte subset proinflammatory responses within the lung microvasculature by the p38 MAPK/MK2 pathway

Margination and activation of monocytes within the pulmonary microcirculation contribute substantially to the development of acute lung injury in mice. The enhanced LPS-induced TNF expression exhibited by Gr-1(high) compared with Gr-1(low) monocytes within the lung microvasculature suggests differen...

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Detalles Bibliográficos
Autores principales: O'Dea, Kieran P., Dokpesi, Justina O., Tatham, Kate C., Wilson, Michael R., Takata, Masao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213987/
https://www.ncbi.nlm.nih.gov/pubmed/21873449
http://dx.doi.org/10.1152/ajplung.00092.2011