Transgenic Mice Over-Expressing ET-1 in the Endothelial Cells Develop Systemic Hypertension with Altered Vascular Reactivity

Endothelin-1 (ET-1) is a potent vasoconstrictor involved in the regulation of vascular tone and implicated in hypertension. However, the role of small blood vessels endothelial ET-1 in hypertension remains unclear. The present study investigated the effect of chronic over-expression of endothelial E...

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Detalles Bibliográficos
Autores principales: Leung, Justin Wai-Chung, Wong, Wing Tak, Koon, Hon Wai, Mo, Fong Ming, Tam, Sidney, Huang, Yu, Vanhoutte, Paul M., Chung, Stephen Sum Man, Chung, Sookja Kim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3214015/
https://www.ncbi.nlm.nih.gov/pubmed/22096514
http://dx.doi.org/10.1371/journal.pone.0026994

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3214015/
https://www.ncbi.nlm.nih.gov/pubmed/22096514
http://dx.doi.org/10.1371/journal.pone.0026994

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