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A Secreted Form of the Asialoglycoprotein Receptor, sH2a, as a Novel Potential Noninvasive Marker for Liver Fibrosis

BACKGROUND AND AIM: The human asialoglycoprotein receptor is a membrane heterooligomer expressed exclusively in hepatocytes. A soluble secreted form, sH2a, arises, not by shedding at the cell surface, but by intracellular cleavage of its membrane-bound precursor, which is encoded by an alternatively...

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Detalles Bibliográficos
Autores principales: Veselkin, Elena, Kondratyev, Maria, Lurie, Yoav, Ron, Efrat, Santo, Moshe, Reif, Shimon, Elashvili, Irma, Bar, Lana, Lederkremer, Gerardo Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3214029/
https://www.ncbi.nlm.nih.gov/pubmed/22096539
http://dx.doi.org/10.1371/journal.pone.0027210