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Origins and Evolution of the HET-s Prion-Forming Protein: Searching for Other Amyloid-Forming Solenoids

The HET-s prion-forming domain from the filamentous fungus Podospora anserina is gaining considerable interest since it yielded the first well-defined atomic structure of a functional amyloid fibril. This structure has been identified as a left-handed beta solenoid with a triangular hydrophobic core...

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Detalles Bibliográficos
Autores principales: Gendoo, Deena M. A., Harrison, Paul M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3214033/
https://www.ncbi.nlm.nih.gov/pubmed/22096554
http://dx.doi.org/10.1371/journal.pone.0027342