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Temperature-Dependence of Weibel-Palade Body Exocytosis and Cell Surface Dispersal of von Willebrand Factor and Its Propolypeptide

BACKGROUND: Weibel-Palade bodies (WPB) are endothelial cell (EC) specific secretory organelles containing Von Willebrand factor (VWF). The temperature-dependence of Ca(2+)-driven WPB exocytosis is not known, although indirect evidence suggests that WPB exocytosis may occur at very low temperatures....

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Detalles Bibliográficos
Autores principales: Hewlett, Lindsay, Zupančič, Gregor, Mashanov, Gregory, Knipe, Laura, Ogden, David, Hannah, Matthew J., Carter, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3214045/
https://www.ncbi.nlm.nih.gov/pubmed/22096550
http://dx.doi.org/10.1371/journal.pone.0027314