Effect of Protein Kinase C delta (PKC-δ) Inhibition on the Transcriptome of Normal and Systemic Sclerosis Human Dermal Fibroblasts In Vitro

Previous studies demonstrated that protein kinase C- δ (PKC-δ) inhibition with the selective inhibitor, rottlerin, resulted in potent downregulation of type I collagen expression and production in normal human dermal fibroblasts and abrogated the exaggerated type I collagen production and expression...

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Detalles Bibliográficos
Autores principales: Wermuth, Peter J., Addya, Sankar, Jimenez, Sergio A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3214051/
https://www.ncbi.nlm.nih.gov/pubmed/22096525
http://dx.doi.org/10.1371/journal.pone.0027110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3214051/
https://www.ncbi.nlm.nih.gov/pubmed/22096525
http://dx.doi.org/10.1371/journal.pone.0027110

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