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Dynamic Microtubules Promote Synaptic NMDA Receptor-Dependent Spine Enlargement

Most excitatory synaptic terminals in the brain impinge on dendritic spines. We and others have recently shown that dynamic microtubules (MTs) enter spines from the dendritic shaft. However, a direct role for MTs in long-lasting spine plasticity has yet to be demonstrated and it remains unclear whet...

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Detalles Bibliográficos
Autores principales: Merriam, Elliott B., Lumbard, Derek C., Viesselmann, Chris, Ballweg, Jason, Stevenson, Matthew, Pietila, Lauren, Hu, Xindao, Dent, Erik W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3214068/
https://www.ncbi.nlm.nih.gov/pubmed/22096612
http://dx.doi.org/10.1371/journal.pone.0027688