Cargando…
Dynamic Microtubules Promote Synaptic NMDA Receptor-Dependent Spine Enlargement
Most excitatory synaptic terminals in the brain impinge on dendritic spines. We and others have recently shown that dynamic microtubules (MTs) enter spines from the dendritic shaft. However, a direct role for MTs in long-lasting spine plasticity has yet to be demonstrated and it remains unclear whet...
Autores principales: | Merriam, Elliott B., Lumbard, Derek C., Viesselmann, Chris, Ballweg, Jason, Stevenson, Matthew, Pietila, Lauren, Hu, Xindao, Dent, Erik W. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3214068/ https://www.ncbi.nlm.nih.gov/pubmed/22096612 http://dx.doi.org/10.1371/journal.pone.0027688 |
Ejemplares similares
-
Nucleofection and Primary Culture of Embryonic Mouse Hippocampal and Cortical Neurons
por: Viesselmann, Christopher, et al.
Publicado: (2011) -
Transport of a kinesin-cargo pair along microtubules into dendritic spines undergoing synaptic plasticity
por: McVicker, Derrick P., et al.
Publicado: (2016) -
Of microtubules and memory: implications for microtubule dynamics in dendrites and spines
por: Dent, Erik W.
Publicado: (2017) -
A Ca(2+)-Based Computational Model for NMDA Receptor-Dependent Synaptic Plasticity at Individual Post-Synaptic Spines in the Hippocampus
por: Rackham, Owen J. L., et al.
Publicado: (2010) -
Amyloid Beta-Mediated Changes in Synaptic Function and Spine Number of Neocortical Neurons Depend on NMDA Receptors
por: Back, Michaela K., et al.
Publicado: (2021)