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Atypical Scrapie Isolates Involve a Uniform Prion Species with a Complex Molecular Signature

The pathobiology of atypical scrapie, a prion disease affecting sheep and goats, is still poorly understood. In a previous study, we demonstrated that atypical scrapie affecting small ruminants in Switzerland differs in the neuroanatomical distribution of the pathological prion protein (PrP(d)). To...

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Detalles Bibliográficos
Autores principales: Götte, Dorothea R., Benestad, Sylvie L., Laude, Hubert, Zurbriggen, Andreas, Oevermann, Anna, Seuberlich, Torsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3214077/
https://www.ncbi.nlm.nih.gov/pubmed/22096587
http://dx.doi.org/10.1371/journal.pone.0027510