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Anti-CD20 B-cell depletion enhances monocyte reactivity in neuroimmunological disorders

BACKGROUND: Clinical trials evaluating anti-CD20-mediated B-cell depletion in multiple sclerosis (MS) and neuromyelitis optica (NMO) generated encouraging results. Our recent studies in the MS model experimental autoimmune encephalomyelitis (EAE) attributed clinical benefit to extinction of activate...

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Detalles Bibliográficos
Autores principales: Lehmann-Horn, Klaus, Schleich, Eva, Hertzenberg, Deetje, Hapfelmeier, Alexander, Kümpfel, Tania, von Bubnoff, Nikolas, Hohlfeld, Reinhard, Berthele, Achim, Hemmer, Bernhard, Weber, Martin S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3214191/
https://www.ncbi.nlm.nih.gov/pubmed/22027448
http://dx.doi.org/10.1186/1742-2094-8-146