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Anti-CD20 B-cell depletion enhances monocyte reactivity in neuroimmunological disorders
BACKGROUND: Clinical trials evaluating anti-CD20-mediated B-cell depletion in multiple sclerosis (MS) and neuromyelitis optica (NMO) generated encouraging results. Our recent studies in the MS model experimental autoimmune encephalomyelitis (EAE) attributed clinical benefit to extinction of activate...
Autores principales: | Lehmann-Horn, Klaus, Schleich, Eva, Hertzenberg, Deetje, Hapfelmeier, Alexander, Kümpfel, Tania, von Bubnoff, Nikolas, Hohlfeld, Reinhard, Berthele, Achim, Hemmer, Bernhard, Weber, Martin S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3214191/ https://www.ncbi.nlm.nih.gov/pubmed/22027448 http://dx.doi.org/10.1186/1742-2094-8-146 |
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