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Hepatitis B virus core promoter mutations G1613A and C1653T are significantly associated with hepatocellular carcinoma in genotype C HBV-infected patients

BACKGROUND: Hepatitis B virus (HBV) is a major cause of hepatocarcinogenesis. To identify mutations relevant to hepatocellular carcinoma (HCC) development, we compared the full genome sequences of HBV from the sera of patients with and without HCC. METHODS: We compared the full genome sequences of H...

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Detalles Bibliográficos
Autores principales: Tatsukawa, Masashi, Takaki, Akinobu, Shiraha, Hidenori, Koike, Kazuko, Iwasaki, Yoshiaki, Kobashi, Haruhiko, Fujioka, Shin-Ichi, Sakaguchi, Kohsaku, Yamamoto, Kazuhide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3214198/
https://www.ncbi.nlm.nih.gov/pubmed/22014121
http://dx.doi.org/10.1186/1471-2407-11-458