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Impaired Rho GTPase activation abrogates cell polarization and migration in macrophages with defective lipolysis
Infiltration of monocytes and macrophages into the site of inflammation is critical in the progression of inflammatory diseases such as atherosclerosis. Cell migration is dependent on the continuous organization of the actin cytoskeleton, which is regulated by members of the small Rho GTPase family...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SP Birkhäuser Verlag Basel
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3214256/ https://www.ncbi.nlm.nih.gov/pubmed/21533980 http://dx.doi.org/10.1007/s00018-011-0688-4 |