Impaired Rho GTPase activation abrogates cell polarization and migration in macrophages with defective lipolysis

Infiltration of monocytes and macrophages into the site of inflammation is critical in the progression of inflammatory diseases such as atherosclerosis. Cell migration is dependent on the continuous organization of the actin cytoskeleton, which is regulated by members of the small Rho GTPase family...

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Detalles Bibliográficos
Autores principales: Aflaki, Elma, Balenga, Nariman A. B., Luschnig-Schratl, Petra, Wolinski, Heimo, Povoden, Silvia, Chandak, Prakash G., Bogner-Strauss, Juliane G., Eder, Sandra, Konya, Viktoria, Kohlwein, Sepp-Dieter, Heinemann, Akos, Kratky, Dagmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SP Birkhäuser Verlag Basel 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3214256/
https://www.ncbi.nlm.nih.gov/pubmed/21533980
http://dx.doi.org/10.1007/s00018-011-0688-4

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