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Sox4 mediates Tbx3 transcriptional regulation of the gap junction protein Cx43

Tbx3, a T-box transcription factor, regulates key steps in development of the heart and other organ systems. Here, we identify Sox4 as an interacting partner of Tbx3. Pull-down and nuclear retention assays verify this interaction and in situ hybridization reveals Tbx3 and Sox4 to co-localize extensi...

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Detalles Bibliográficos
Autores principales: Boogerd, C. J. J., Wong, L. Y. E., van den Boogaard, M., Bakker, M. L., Tessadori, F., Bakkers, J., ‘t Hoen, P. A. C., Moorman, A. F., Christoffels, V. M., Barnett, P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SP Birkhäuser Verlag Basel 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3214269/
https://www.ncbi.nlm.nih.gov/pubmed/21538160
http://dx.doi.org/10.1007/s00018-011-0693-7