5′CAG and 5′CTG Repeats Create Differential Impediment to the Progression of a Minimal Reconstituted T4 Replisome Depending on the Concentration of dNTPs

Instability of repetitive sequences originates from strand misalignment during repair or replicative DNA synthesis. To investigate the activity of reconstituted T4 replisomes across trinucleotide repeats (TNRs) during leading strand DNA synthesis, we developed a method to build replication miniforks...

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Detalles Bibliográficos
Autores principales: Delagoutte, Emmanuelle, Baldacci, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3214698/
https://www.ncbi.nlm.nih.gov/pubmed/22096622
http://dx.doi.org/10.4061/2011/213824

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3214698/
https://www.ncbi.nlm.nih.gov/pubmed/22096622
http://dx.doi.org/10.4061/2011/213824

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