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Inactivation of Aconitase by Tetrahydrobiopterin in DArgic Cells: Relevance to PD

Oxidative damage is thought to be a major cause of the progression of dopamine (DA)rgic neurodegeneration as in Parkinson's disease. We have previously reported that tetrahydrobiopterin (BH4), an endogenous molecule required for DA synthesis, exerts oxidative stress to DA-producing cells and fa...

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Detalles Bibliográficos
Autores principales: Yoon, Nam Soo, Cho, Yuri, Lee, So Yeon, Choi, Hyun Jin, Hwang, Onyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Brain and Neural Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3214796/
https://www.ncbi.nlm.nih.gov/pubmed/22110338
http://dx.doi.org/10.5607/en.2010.19.1.23