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Activation of PI3K/AKT and ERK MAPK signal pathways is required for the induction of lytic cycle replication of Kaposi's Sarcoma-associated herpesvirus by herpes simplex virus type 1

BACKGROUND: Kaposi's sarcoma-associated herpesvirus (KSHV) is causally linked to several acquired immunodeficiency syndrome-related malignancies, including Kaposi's sarcoma (KS), primary effusion lymphoma (PEL) and a subset of multicentric Castleman's disease. Regulation of viral lyti...

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Detalles Bibliográficos
Autores principales: Qin, Di, Feng, Ninghan, Fan, Weifei, Ma, Xinting, Yan, Qin, Lv, Zhigang, Zeng, Yi, Zhu, Jianzhong, Lu, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215226/
https://www.ncbi.nlm.nih.gov/pubmed/22032493
http://dx.doi.org/10.1186/1471-2180-11-240