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Canalization effect in the coagulation cascade and the interindividual variability of oral anticoagulant response. a simulation Study

BACKGROUND: Increasing the predictability and reducing the rate of side effects of oral anticoagulant treatment (OAT) requires further clarification of the cause of about 50% of the interindividual variability of OAT response that is currently unaccounted for. We explore numerically the hypothesis t...

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Detalles Bibliográficos
Autores principales: Corlan, Alexandru D, Ross, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215663/
https://www.ncbi.nlm.nih.gov/pubmed/22082142
http://dx.doi.org/10.1186/1742-4682-8-37