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Canalization effect in the coagulation cascade and the interindividual variability of oral anticoagulant response. a simulation Study
BACKGROUND: Increasing the predictability and reducing the rate of side effects of oral anticoagulant treatment (OAT) requires further clarification of the cause of about 50% of the interindividual variability of OAT response that is currently unaccounted for. We explore numerically the hypothesis t...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215663/ https://www.ncbi.nlm.nih.gov/pubmed/22082142 http://dx.doi.org/10.1186/1742-4682-8-37 |