Mitochondrial-Associated Cell Death Mechanisms Are Reset to an Embryonic-Like State in Aged Donor-Derived iPS Cells Harboring Chromosomal Aberrations

Somatic cells reprogrammed into induced pluripotent stem cells (iPSCs) acquire features of human embryonic stem cells (hESCs) and thus represent a promising source for cellular therapy of debilitating diseases, such as age-related disorders. However, reprogrammed cell lines have been found to harbor...

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Detalles Bibliográficos
Autores principales: Prigione, Alessandro, Hossini, Amir M., Lichtner, Björn, Serin, Akdes, Fauler, Beatrix, Megges, Matthias, Lurz, Rudi, Lehrach, Hans, Makrantonaki, Eugenia, Zouboulis, Christos C., Adjaye, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215709/
https://www.ncbi.nlm.nih.gov/pubmed/22110631
http://dx.doi.org/10.1371/journal.pone.0027352

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215709/
https://www.ncbi.nlm.nih.gov/pubmed/22110631
http://dx.doi.org/10.1371/journal.pone.0027352

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