Probing the Limits of Aptamer Affinity with a Microfluidic SELEX Platform

Nucleic acid-based aptamers offer many potential advantages relative to antibodies and other protein-based affinity reagents, including facile chemical synthesis, reversible folding, improved thermal stability and lower cost. However, their selection requires significant time and resources and selec...

Descripción completa

Detalles Bibliográficos
Autores principales: Ahmad, Kareem M., Oh, Seung Soo, Kim, Seon, McClellen, Forrest M., Xiao, Yi, Soh, H. Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215713/
https://www.ncbi.nlm.nih.gov/pubmed/22110600
http://dx.doi.org/10.1371/journal.pone.0027051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215713/
https://www.ncbi.nlm.nih.gov/pubmed/22110600
http://dx.doi.org/10.1371/journal.pone.0027051

Ejemplares similares