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A Splice Isoform of DNedd4, DNedd4-Long, Negatively Regulates Neuromuscular Synaptogenesis and Viability in Drosophila

BACKGROUND: Neuromuscular (NM) synaptogenesis is a tightly regulated process. We previously showed that in flies, Drosophila Nedd4 (dNedd4/dNedd4S) is required for proper NM synaptogenesis by promoting endocytosis of commissureless from the muscle surface, a pre-requisite step for muscle innervation...

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Detalles Bibliográficos
Autores principales: Zhong, Yunan, Shtineman-Kotler, Alina, Nguyen, Leo, Iliadi, Konstantin G., Boulianne, Gabrielle L., Rotin, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215714/
https://www.ncbi.nlm.nih.gov/pubmed/22110599
http://dx.doi.org/10.1371/journal.pone.0027007