Cargando…

Dysferlin Forms a Dimer Mediated by the C2 Domains and the Transmembrane Domain In Vitro and in Living Cells

Dysferlin was previously identified as a key player in muscle membrane repair and its deficiency leads to the development of muscular dystrophy and cardiomyopathy. However, little is known about the oligomerization of this protein in the plasma membrane. Here we report for the first time that dysfer...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Li, Pallikkuth, Sandeep, Hou, Zhanjia, Mignery, Gregory A., Robia, Seth L., Han, Renzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215728/
https://www.ncbi.nlm.nih.gov/pubmed/22110769
http://dx.doi.org/10.1371/journal.pone.0027884