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Dysferlin Forms a Dimer Mediated by the C2 Domains and the Transmembrane Domain In Vitro and in Living Cells
Dysferlin was previously identified as a key player in muscle membrane repair and its deficiency leads to the development of muscular dystrophy and cardiomyopathy. However, little is known about the oligomerization of this protein in the plasma membrane. Here we report for the first time that dysfer...
Autores principales: | Xu, Li, Pallikkuth, Sandeep, Hou, Zhanjia, Mignery, Gregory A., Robia, Seth L., Han, Renzhi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215728/ https://www.ncbi.nlm.nih.gov/pubmed/22110769 http://dx.doi.org/10.1371/journal.pone.0027884 |
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