The PDZ-Ligand and Src-Homology Type 3 Domains of Epidemic Avian Influenza Virus NS1 Protein Modulate Human Src Kinase Activity during Viral Infection

The Non-structural 1 (NS1) protein of avian influenza (AI) viruses is important for pathogenicity. Here, we identify a previously unrecognized tandem PDZ-ligand (TPL) domain in the extreme carboxy terminus of NS1 proteins from a subset of globally circulating AI viruses. By using protein arrays we h...

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Detalles Bibliográficos
Autores principales: Bavagnoli, Laura, Dundon, William G., Garbelli, Anna, Zecchin, Bianca, Milani, Adelaide, Parakkal, Geetha, Baldanti, Fausto, Paolucci, Stefania, Volmer, Romain, Tu, Yizeng, Wu, Chuanyue, Capua, Ilaria, Maga, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215730/
https://www.ncbi.nlm.nih.gov/pubmed/22110760
http://dx.doi.org/10.1371/journal.pone.0027789

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215730/
https://www.ncbi.nlm.nih.gov/pubmed/22110760
http://dx.doi.org/10.1371/journal.pone.0027789

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