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GSK3β Is Involved in the Relief of Mitochondria Pausing in a Tau-Dependent Manner

Mitochondrial trafficking deficits have been implicated in the pathogenesis of several neurological diseases, including Alzheimer's disease (AD). The Ser/Thre kinase GSK3β is believed to play a fundamental role in AD pathogenesis. Given that GSK3β substrates include Tau protein, here we studied...

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Detalles Bibliográficos
Autores principales: Llorens-Martín, María, López-Doménech, Guillermo, Soriano, Eduardo, Avila, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215736/
https://www.ncbi.nlm.nih.gov/pubmed/22110721
http://dx.doi.org/10.1371/journal.pone.0027686