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Expression of DNMT1 and DNMT3a Are Regulated by GLI1 in Human Pancreatic Cancer
BACKGROUND AND AIMS: GLI1, as an indispensable transcriptional factor of Hedgehog signaling pathway, plays an important role in the development of pancreatic cancer (PC). DNA methyltransferases (DNMTs) mediate the methylation of quantity of tumor-related genes. Our study aimed to explore the relatio...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215738/ https://www.ncbi.nlm.nih.gov/pubmed/22110720 http://dx.doi.org/10.1371/journal.pone.0027684 |