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Expression of DNMT1 and DNMT3a Are Regulated by GLI1 in Human Pancreatic Cancer

BACKGROUND AND AIMS: GLI1, as an indispensable transcriptional factor of Hedgehog signaling pathway, plays an important role in the development of pancreatic cancer (PC). DNA methyltransferases (DNMTs) mediate the methylation of quantity of tumor-related genes. Our study aimed to explore the relatio...

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Detalles Bibliográficos
Autores principales: He, ShanShan, Wang, Feng, Yang, LiJuan, Guo, ChuanYong, Wan, Rong, Ke, AiWu, Xu, Ling, Hu, GuoYong, Xu, XuanFu, Shen, Jie, Wang, XingPeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215738/
https://www.ncbi.nlm.nih.gov/pubmed/22110720
http://dx.doi.org/10.1371/journal.pone.0027684