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Polymorphisms in the Innate Immune IFIH1 Gene, Frequency of Enterovirus in Monthly Fecal Samples during Infancy, and Islet Autoimmunity

Interferon induced with helicase C domain 1 (IFIH1) senses and initiates antiviral activity against enteroviruses. Genetic variants of IFIH1, one common and four rare SNPs have been associated with lower risk for type 1 diabetes. Our aim was to test whether these type 1 diabetes-associated IFIH1 pol...

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Detalles Bibliográficos
Autores principales: Witsø, Elisabet, Tapia, German, Cinek, Ondrej, Pociot, Flemming Michael, Stene, Lars C., Rønningen, Kjersti S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215739/
https://www.ncbi.nlm.nih.gov/pubmed/22110759
http://dx.doi.org/10.1371/journal.pone.0027781