Suppression of Neurotoxic Lesion-Induced Seizure Activity: Evidence for a Permanent Role for the Hippocampus in Contextual Memory

Damage to the hippocampus (HPC) using the excitotoxin N-methyl-D-aspartate (NMDA) can cause retrograde amnesia for contextual fear memory. This amnesia is typically attributed to loss of cells in the HPC. However, NMDA is also known to cause intense neuronal discharge (seizure activity) during the h...

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Detalles Bibliográficos
Autores principales: Sparks, Fraser T., Lehmann, Hugo, Hernandez, Khadaryna, Sutherland, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215748/
https://www.ncbi.nlm.nih.gov/pubmed/22110648
http://dx.doi.org/10.1371/journal.pone.0027426

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215748/
https://www.ncbi.nlm.nih.gov/pubmed/22110648
http://dx.doi.org/10.1371/journal.pone.0027426

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