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Post-traumatic hypoxia exacerbates neurological deficit, neuroinflammation and cerebral metabolism in rats with diffuse traumatic brain injury

BACKGROUND: The combination of diffuse brain injury with a hypoxic insult is associated with poor outcomes in patients with traumatic brain injury. In this study, we investigated the impact of post-traumatic hypoxia in amplifying secondary brain damage using a rat model of diffuse traumatic axonal i...

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Detalles Bibliográficos
Autores principales: Yan, Edwin B, Hellewell, Sarah C, Bellander, Bo-Michael, Agyapomaa, Doreen A, Morganti-Kossmann, M Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215944/
https://www.ncbi.nlm.nih.gov/pubmed/22034986
http://dx.doi.org/10.1186/1742-2094-8-147