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Requirement for Pdx1 in specification of latent endocrine progenitors in zebrafish
BACKGROUND: Insulin-producing beta cells emerge during pancreas development in two sequential waves. Recently described later-forming beta cells in zebrafish show high similarity to second wave mammalian beta cells in developmental capacity. Loss-of-function studies in mouse and zebrafish demonstrat...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215967/ https://www.ncbi.nlm.nih.gov/pubmed/22034951 http://dx.doi.org/10.1186/1741-7007-9-75 |