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Requirement for Pdx1 in specification of latent endocrine progenitors in zebrafish

BACKGROUND: Insulin-producing beta cells emerge during pancreas development in two sequential waves. Recently described later-forming beta cells in zebrafish show high similarity to second wave mammalian beta cells in developmental capacity. Loss-of-function studies in mouse and zebrafish demonstrat...

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Detalles Bibliográficos
Autores principales: Kimmel, Robin A, Onder, Lucas, Wilfinger, Armin, Ellertsdottir, Elin, Meyer, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215967/
https://www.ncbi.nlm.nih.gov/pubmed/22034951
http://dx.doi.org/10.1186/1741-7007-9-75