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The docking protein p130Cas regulates cell sensitivity to proteasome inhibition
BACKGROUND: The focal adhesion protein p130Cas (Cas) activates multiple intracellular signaling pathways upon integrin or growth factor receptor ligation. Full-length Cas frequently promotes cell survival and migration, while its C-terminal fragment (Cas-CT) produced upon intracellular proteolysis i...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215977/ https://www.ncbi.nlm.nih.gov/pubmed/22034875 http://dx.doi.org/10.1186/1741-7007-9-73 |