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The contribution of activated astrocytes to Aβ production: Implications for Alzheimer's disease pathogenesis
BACKGROUND: β-Amyloid (Aβ) plays a central role in Alzheimer's disease (AD) pathogenesis. Neurons are major sources of Aβ in the brain. However, astrocytes outnumber neurons by at least five-fold. Thus, even a small level of astrocytic Aβ production could make a significant contribution to Aβ b...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216000/ https://www.ncbi.nlm.nih.gov/pubmed/22047170 http://dx.doi.org/10.1186/1742-2094-8-150 |