PI3K/AKT is involved in mediating survival signals that rescue Ewing tumour cells from fibroblast growth factor 2-induced cell death

While in vitro studies had shown that fibroblast growth factor 2 (FGF2) can induce cell death in Ewing tumours, it remained unclear how Ewing tumour cells survive in vivo within a FGF2-rich microenvironment. Serum- and integrin-mediated survival signals were, therefore, studied in adherent monolayer...

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Detalles Bibliográficos
Autores principales: Hotfilder, M, Sondermann, P, Senß, A, van Valen, F, Jürgens, H, Vormoor, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2005
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216036/
https://www.ncbi.nlm.nih.gov/pubmed/15685229
http://dx.doi.org/10.1038/sj.bjc.6602384

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216036/
https://www.ncbi.nlm.nih.gov/pubmed/15685229
http://dx.doi.org/10.1038/sj.bjc.6602384

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