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Mitochondrial Dysfunction and β-Cell Failure in Type 2 Diabetes Mellitus
Type 2 diabetes mellitus (T2DM) is the most common human endocrine disease and is characterized by peripheral insulin resistance and pancreatic islet β-cell failure. Accumulating evidence indicates that mitochondrial dysfunction is a central contributor to β-cell failure in the evolution of T2DM. As...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216264/ https://www.ncbi.nlm.nih.gov/pubmed/22110477 http://dx.doi.org/10.1155/2012/703538 |