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Factors Affecting EWS-FLI1 Activity in Ewing's Sarcoma

Ewing's sarcoma family tumors (ESFT) are characterized by specific chromosomal translocations, which give rise to EWS-ETS chimeric proteins. These aberrant transcription factors are the main pathogenic drivers of ESFT. Elucidation of the factors influencing EWS-ETS expression and/or activity wi...

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Detalles Bibliográficos
Autores principales: Herrero-Martin, David, Fourtouna, Argyro, Niedan, Stephan, Riedmann, Lucia T., Schwentner, Raphaela, Aryee, Dave N. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216314/
https://www.ncbi.nlm.nih.gov/pubmed/22135504
http://dx.doi.org/10.1155/2011/352580