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Pannexin 3 functions as an ER Ca(2+) channel, hemichannel, and gap junction to promote osteoblast differentiation

The pannexin proteins represent a new gap junction family. However, the cellular functions of pannexins remain largely unknown. Here, we demonstrate that pannexin 3 (Panx3) promotes differentiation of osteoblasts and ex vivo growth of metatarsals. Panx3 expression was induced during osteogenic diffe...

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Detalles Bibliográficos
Autores principales: Ishikawa, Masaki, Iwamoto, Tsutomu, Nakamura, Takashi, Doyle, Andrew, Fukumoto, Satoshi, Yamada, Yoshihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216329/
https://www.ncbi.nlm.nih.gov/pubmed/21690309
http://dx.doi.org/10.1083/jcb.201101050