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Pannexin 3 functions as an ER Ca(2+) channel, hemichannel, and gap junction to promote osteoblast differentiation
The pannexin proteins represent a new gap junction family. However, the cellular functions of pannexins remain largely unknown. Here, we demonstrate that pannexin 3 (Panx3) promotes differentiation of osteoblasts and ex vivo growth of metatarsals. Panx3 expression was induced during osteogenic diffe...
Autores principales: | Ishikawa, Masaki, Iwamoto, Tsutomu, Nakamura, Takashi, Doyle, Andrew, Fukumoto, Satoshi, Yamada, Yoshihiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216329/ https://www.ncbi.nlm.nih.gov/pubmed/21690309 http://dx.doi.org/10.1083/jcb.201101050 |
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