Cargando…

SPARC promotes pericyte recruitment via inhibition of endoglin-dependent TGF-β1 activity

Pericytes migrate to nascent vessels and promote vessel stability. Recently, we reported that secreted protein acidic and rich in cysteine (SPARC)–deficient mice exhibited decreased pericyte-associated vessels in an orthotopic model of pancreatic cancer, suggesting that SPARC influences pericyte beh...

Descripción completa

Detalles Bibliográficos
Autores principales: Rivera, Lee B., Brekken, Rolf A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216331/
https://www.ncbi.nlm.nih.gov/pubmed/21708981
http://dx.doi.org/10.1083/jcb.201011143