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SPARC promotes pericyte recruitment via inhibition of endoglin-dependent TGF-β1 activity
Pericytes migrate to nascent vessels and promote vessel stability. Recently, we reported that secreted protein acidic and rich in cysteine (SPARC)–deficient mice exhibited decreased pericyte-associated vessels in an orthotopic model of pancreatic cancer, suggesting that SPARC influences pericyte beh...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Rockefeller University Press
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216331/ https://www.ncbi.nlm.nih.gov/pubmed/21708981 http://dx.doi.org/10.1083/jcb.201011143 |