Cargando…

RA–RAR-β counteracts myelin-dependent inhibition of neurite outgrowth via Lingo-1 repression

After an acute central nervous system injury, axonal regeneration is limited as the result of a lack of neuronal intrinsic competence and the presence of extrinsic inhibitory signals. The injury fragments the myelin neuronal insulating layer, releasing extrinsic inhibitory molecules to signal throug...

Descripción completa

Detalles Bibliográficos
Autores principales: Puttagunta, Radhika, Schmandke, André, Floriddia, Elisa, Gaub, Perrine, Fomin, Natalie, Ghyselinck, Norbert B., Di Giovanni, Simone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216335/
https://www.ncbi.nlm.nih.gov/pubmed/21690307
http://dx.doi.org/10.1083/jcb.201102066