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RA–RAR-β counteracts myelin-dependent inhibition of neurite outgrowth via Lingo-1 repression
After an acute central nervous system injury, axonal regeneration is limited as the result of a lack of neuronal intrinsic competence and the presence of extrinsic inhibitory signals. The injury fragments the myelin neuronal insulating layer, releasing extrinsic inhibitory molecules to signal throug...
Autores principales: | Puttagunta, Radhika, Schmandke, André, Floriddia, Elisa, Gaub, Perrine, Fomin, Natalie, Ghyselinck, Norbert B., Di Giovanni, Simone |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216335/ https://www.ncbi.nlm.nih.gov/pubmed/21690307 http://dx.doi.org/10.1083/jcb.201102066 |
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