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SplitCore: An exceptionally versatile viral nanoparticle for native whole protein display regardless of 3D structure
Nanoparticles displaying native proteins are attractive for many applications, including vaccinology. Virus-based nanoparticles are easily tailored by genetic means, commonly by inserting heterologous sequences into surface-exposed loops. The strategy works well with short peptides but is incompatib...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216493/ https://www.ncbi.nlm.nih.gov/pubmed/22355524 http://dx.doi.org/10.1038/srep00005 |