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SplitCore: An exceptionally versatile viral nanoparticle for native whole protein display regardless of 3D structure

Nanoparticles displaying native proteins are attractive for many applications, including vaccinology. Virus-based nanoparticles are easily tailored by genetic means, commonly by inserting heterologous sequences into surface-exposed loops. The strategy works well with short peptides but is incompatib...

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Detalles Bibliográficos
Autores principales: Walker, Andreas, Skamel, Claudia, Nassal, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216493/
https://www.ncbi.nlm.nih.gov/pubmed/22355524
http://dx.doi.org/10.1038/srep00005